Practicum B: Transcriptomics and Metabolomics is a rigorous laboratory-based course tailored for graduate students in the genomic medicine track. This practicum focuses on equipping students with the practical skills and analytical expertise required to explore the dynamic fields of transcriptomics — the study of RNA transcripts. Students will be immersed in the end-to-end processes of transcriptomic. They will learn about the basics of RNA related laboratory work such as RNA extraction, reverse transcription techniques, and quantitative RTPCR as well as more advanced approaches microarrays and the most popular RNA sequencing technologies. They will also be trained to learn about various databases, data processing, visualization, and interpretation of expression patterns. The students will also be introduced to basics of systems biology, basic analyses and data integration of various omics in the context of genomic medicine. Real-world applications of these powerful omics technologies will be a key component of the course, with a particular focus on their use in the discovery of disease biomarkers, the elucidation of disease mechanisms, and the development of personalized therapeutic strategies. The practical skills are complemented by a series of lab lectures, student presentations based on latest developments in the field aimed at honing critical thinking and basic understanding of integrated omics approaches. Students will also be exposed to gene networks and pathway analyses and will have opportunities to present their work, encouraging the development of communication skills important for scientific dialogue and collaboration. By the conclusion of Practicum B, students will have developed a clear and strong understanding of the methodologies and applications of transcriptomics and its integration into the research and clinical settings.
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