MBS 562: Pathophysiology and aetiology of bleeding and thrombosis

The course will discuss the biological mechanism(s) underlying acquired and genetic risk factors for VTE that express disease phenotypes (obesity, spontaneous thrombosis) or that lack genes key to the mechanistic pathways of interest. Expose the student to relevant biochemical and molecular technologies for the diagnosis of different thrombosis and thrombophilia. This course combines emerging modern laboratory diagnostic techniques and its application to the management of venous thromboembolic events. It will also provide an in-depth look at the pathophysiology and treatment of inherited and acquired bleeding disorders, with a special focus on von Willebrand disease and haemophilia and exposure to rare bleeding disorders. Also there will be exposure to different anticoagulation drugs and the methods of monitoring patients on these therapies. There will be a practical part of this course where the students will be involved in testing patients with thrombosis and thrombophilia with possible attendance of a clinic to expose to clinical management of patients with thrombosis